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Journal of Family and Reproductive Health، جلد ۲، شماره ۳، صفحات ۱۵۹-۱۶۲
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی The Role of Serum Uric Acid in Preeclampsia
چکیده انگلیسی مقاله Objective: The goal of this study was to assess the utility of serum uric acid in preeclampsia diagnosis and its correlation with some maternal and fetal outcomes. Materials and methods: A case-control study was performed on 26 term pregnant women with preeclampsia and 52 normal pregnant women. Serum uric acid, platelet count, hematocrit, gestational age, and birth weight of all patients were measured. Data distribution was assessed with the one sample Kolmogorov-Smirnov test. Mann-Whitney U test was used to assess differences between groups. Correlations between plasma uric acid and other parameters were evaluated with the Spearman’s Rho or Pearson correlation test, where appropriated. Receiver-operating characteristics (ROC) curves were used to assess the ability of plasma uric acid to distinguish the preeclampsia from normal subjects. Significance was set at P< 0.05. Results: The mean level of plasma uric acid was 5.8 (+2) mg/dl in cases and 4.9 mg/dl in controls (P=0.04). ROC curve analysis demonstrates the absence of obvious cut off point for plasma uric acid to distinguish preeclampsia. Sensitivity and specificity for uric acid level of 5.5 mg/dl were 61.5% and 78.8%, respectively. There was no significant linear correlation between the plasma uric acid level and other measured parameters in each group. Conclusion: On the basis of our data, the clinical utility of measuring serum uric acid levels in diagnosing preeclampsia is limited.
کلیدواژه‌های انگلیسی مقاله Uric acid,Preeclampsia,Pregnancy Diagnostic test
نویسندگان مقاله امیر طایفی | amir taefi
department of obstetrics and gynecology, shariati hospital, tehran university of medical sciences

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

اشرف سادات جمال | ashraf sadat jamal
department of obstetrics and gynecology, shariati hospital, tehran university of medical sciences

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

هومان دلاوری | human delavari
department of obstetrics and gynecology, shariati hospital, tehran university of medical sciences

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

نشانی اینترنتی http://jfrh.tums.ac.ir/index.php/jfrh/article/view/51
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Articles
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