| چکیده انگلیسی مقاله |
Atopic Eczema (AE) is a chronic inflammatory skin disease that affects children and adults, and alters quality of life. Previous studies have suggested several socio-demographic and environmental factors related to the prevalence of AE and other allergic diseases, including acetaminophen use. In the present study, we report the rates of isolated AE, AE associated with asthma and AE associated with rhinitis among 13- to 14-year-old Spanish adolescents and the level of association of these conditions with the use of acetaminophen. We analyzed Spanish data from a cross-sectional Phase 3 study within ISAAC. A total of 28,717 adolescents completed the Phase 3 written questionnaire by answering questions for acetaminophen use and on asthma, rhinitis and AE symptoms. We observed an association between acetaminophen use and AE among the adolescents who had used acetaminophen in the previous month. Furthermore, the prevalence rate increased with the number of allergic processes: for AE alone, the adjusted Prevalence Ratio (aPR) was 1.81 and for AE associated with rhinitis or with asthma, aPRs were 2.20 and 3.03, respectively. We conclude that acetaminophen use in childhood may be an important factor associated with development and/or maintenance of AE and other allergic diseases. |
| نویسندگان مقاله |
maría morales suárez varela | maría morales suárez varela
public and environmental health unit, department of preventive medicine, university of valencia, ciber epidemiology and public health ciberesp , and center for public health research csisp , valencia, spain
luís گارسیا مارکوس | luís garcía marcos
pediatric respiratory and allergy units, “arrixaca” university children’s hospital, university of murcia, and ciber of epidemiology and public health cibersp , murcia, spain
خاویر fuertes فرناندز espinar | javier fuertes fernández espinar
perpetuo socorro” health center, huesca, spain
آلبرتو bercedo sanz | alberto bercedo sanz
meruelo” health center, santander, spain
inés aguinaga ontoso | inés aguinaga ontoso
department of health sciences, public university of navarra, pamplona, spain
کارلوس gonzález دیاز | carlos gonzález díaz
department of pediatrics, basurto hospital, bilbao, spain
ignacio carvajal urueña | ignacio carvajal urueña
la ería” health center, oviedo, asturias princedom health service, asturias, spain
رزا maría busquet monge | rosa maría busquet monge
department of pediatrics, hospital del mar, barcelona, spain
آلبرتو arnedo pena | alberto arnedo pena
centre of public health, regional health authority, castellón, spain
nagore گارسیا de andoin | nagore garcía de andoin
department of pediatrics, “donostia” hospital, san sebastián, guipuzcoa, spain
جوز batlles garrido | josé batlles garrido
department of pediatrics, “torrecárdenas” hospital, almería, spain
alfredo blanco quirós | alfredo blanco quirós
department of pediatrics, university of valladolid, spain
angel lópez silvarrey varela | angel lópez silvarrey varela
maría josé jove foundation, la coruña, spain
گلوریا گارسیا hernández | gloria garcía hernández
pediatric allergy and pulmonology unit. “12 de octubre” university children’s hospital, madrid, spain
ناتالیا gimeno clemente | natalia gimeno clemente
public and environmental health unit, department of preventive medicine, university of valencia, ciber epidemiology and public health ciberesp , and center for public health research csisp , valencia, spain
nuria rubio lópez | nuria rubio lópez
public and environmental health unit, department of preventive medicine, university of valencia, ciber epidemiology and public health ciberesp , and center for public health research csisp , valencia, spain
agustín llopis gonzález | agustín llopis gonzález
public and environmental health unit, department of preventive medicine, university of valencia, ciber epidemiology and public health ciberesp , and center for public health research csisp , valencia, spain
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