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Iranian Journal of Allergy, Asthma and Immunology، جلد ۱۴، شماره ۵، صفحات ۵۴۵-۵۵۱

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عنوان انگلیسی Associated Markers for Adult-onset Allergic Asthma
چکیده انگلیسی مقاله The clinical behavior of asthma varies with age at onset. This study was undertaken to identify associated markers of adult-onset allergic asthma (age ≥20 years).This cross-sectional study compared two groups: 58 patients with asthma onset at < 20 years and 66 with onset at ≥20 years. They were compared depending on results of clinical history, and body mass index (BMI), aeroallergen sensitization, total serum IgE, eosinophil count, asthma control test, and asthma severity level.Ages at first asthma episode were 10.0 ± 6.6 and 33.4 ± 10.5 (p < 0.001) in the < 20 and ≥20 group, respectively. BMI was higher in adult asthmatic subjects (29.8 versus 27.1, P=0.017), but BMI ≥30 kg/m2 was not associated with asthma onset in ≥20 years (odds ratio [OR] = 1.56, 95% confidence interval [CI] 0.759 to 3.211; p= 0.227). After multivariate analysis, allergic rhinitis and IgE ≥150 IU/mL were negatively correlated with asthma onset in ≥20 years old (OR adjusted [ORa] = 0.255, 95% CI 0.078 to 0.837, P= 0.024, and ORa =0.385, 95% CI 0.175 to 0.849, p= 0.018, respectively).Adult-onset allergic asthma was not different from early-onset asthma.
کلیدواژه‌های انگلیسی مقاله Adult,Asthma,Biological markers,Immunoglobulin E

نویسندگان مقاله martín bedolla barajas | martín bedolla barajas
allergy and clinical immunology service, division of internal medicine, hospital civil de guadalajara ”dr. juan i. menchaca”, guadalajara, jalisco, mexico.


jaime morales romero | jaime morales romero
instituto de salud pública, universidad veracruzana, xalapa,veracruz, mexico.


tonatiuh ramses bedolla pulido | tonatiuh ramses bedolla pulido
universidad guadalajara lamar, guadalajara, jalisco, mexico.


lourdes fabiola گارسیا padilla | lourdes fabiola garcía padilla
medical doctor. universidad de guadalajara, guadalajara, jalisco, mexico.


dante hernández colín | dante hernández colín
head of research, hospital civil de guadalajara ”dr. juan i. menchaca”, guadalajara, jalisco, mexico.



نشانی اینترنتی http://ijaai.tums.ac.ir/index.php/ijaai/article/view/604
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Brief Communication
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