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Frontiers in Biomedical Technologies، جلد ۱۱، شماره ۳، صفحات ۴۸۶-۴۹۱
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عنوان انگلیسی Comparison of Lung and Contralateral Scattered Breast Dose between Field-in-Field and Wedge Techniques in Patients with Early Breast Cancer
چکیده انگلیسی مقاله Purpose: This study aims to evaluate the dosimetric result of the Field-In-Field (FIF) plans compared with Tangential Wedged Beams (TWB) plans for whole breast radiotherapy of patients. Materials and Methods: In this survey, we entered fifty patients with breast-conserving surgery and postoperative whole-breast radiotherapy. FIF and a TWB plan were made for each patient to compare dosimetric outcomes. Results: The Homogeneity Index (HI) and Conformity Index (CI) were specified for the evaluation of Planning Target Volume (PTV). The mean dose of the ipsilateral lung and contra-lateral breast for the evaluation of organs at risk dose were used. The FIF plans had significantly lower HI (p < 0.01) and CI (p < 0.01) than those of the TWB plans. It means in the dosimetric comparisons of the PTV, the FIF plans were better than the TWB plans. The V10lung (31.152vs. 32.72%, p < 0.01), V20lung (25.6064vs. 26.6%, p < 0.01) V30lung (17.4% vs. 18.4%, p < 0.01) were lower with the FIF plans compared with those of the TWB plans, with statistical significance. The FIF plans had a lower mean dose for the lung than those of TWB plans (1225.48 vs. 1670.32 cGy) but no statistical significance (p=0.06). The mean dose in the contra-lateral of the breast in FIF plans was lower than in TWB plans (61.666 vs. 163.45 cGy), with statistical significance (p < 0.01). Conclusion: The FIF plans increased the dose homogeneity, and conformity of the target volume for the whole-breast irradiation compared with the TWB plans contralateral breast. Moreover, the doses of organs at risk (ipsilateral lung and contralateral breast) were reduced with FIF plans.
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نویسندگان مقاله | Seraj Adin Zare
Department of Medical Physics, Afzalipour Hospital, Kerman University of Medical Sciences, Kerman, Iran


| Maryam Bahador
Department of Radiotherapy Oncology, Afzalipour Hospital, Kerman University of Medical Sciences, Kerman, Iran


| Samira Yazdani
Department of Medical Physics, Afzalipour Hospital, Kerman University of Medical Sciences, Kerman, Iran
نشانی اینترنتی https://fbt.tums.ac.ir/index.php/fbt/article/view/628
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