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Iranian Journal of Allergy, Asthma and Immunology، جلد ۲۱، شماره ۵، صفحات ۴۹۴-۵۱۱
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عنوان انگلیسی A Comprehensive Overview of Allergen-specific Immunotherapy Types, Recombinant and Natural Extract Allergens in the Diagnosis and Treatment of Allergies
چکیده انگلیسی مقاله Allergen-specific immunotherapy (AIT) involves administering allergen extracts. It is used to desensitize allergic patients. Herbal allergen extracts that are optimum in efficacy and fewest in side effects are still challenging to produce. To overcome these limitations, oral immunotherapy, epicutaneous immunotherapy, intralymphatic immunotherapy, and artificial recombinant allergen preparations have been evaluated. Recombinant allergens have become more popular with the development of molecular diagnostics and therapeutics. Besides food and drug allergens, pollen, fungal spores, and other allergens have been studied. Based on related clinical studies, this comprehensive overview will present the latest perspectives on AIT methods and available allergenic products, as well as discuss the challenges and opportunities for treating allergic disorders.
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نویسندگان مقاله | Soheila Asoudeh Moghanloo
Department of Genetics, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran AND Immunology, Asthma and Allergy Research Institute (IAARI), Tehran University of Medical Sciences, Tehran, Iran


| Mohsen Forouzanfar
Department of Genetics, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran


| Mojtaba Jafarinia
Department of Genetics, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran


| Mohammad Reza Fazlollahi
Immunology, Asthma and Allergy Research Institute (IAARI), Tehran University of Medical Sciences, Tehran, Iran


| Gholam Ali Kardar
Immunology, Asthma and Allergy Research Institute (IAARI), Tehran University of Medical Sciences, Tehran, Iran AND Department of Medical Biotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran
نشانی اینترنتی https://ijaai.tums.ac.ir/index.php/ijaai/article/view/3481
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